Mast Cell Activation Syndrome (MCAS)

Dr Dobie has an interest in mast cell activation syndrome (MCAS).

MCAS is a disorder which is caused by the release of histamine and other mediators from mast cells.

MCAS can cause a wide range of symptoms including dizziness, headaches, flushing, abdominal pain, itching, hives, palpitations, shortness of breath, fainting episodes, fatigue, nausea and diarrhea.

Diagnosis of MCAS can be difficult and is made on the basis of a detailed medical history, physical examination and blood and urine tests.

Treatment of MCAS includes avoidance of known triggers, antihistamines and other measures to reduce inflammation.

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